Senior Management

Gerald T. Proehl Director, President and Chief Executive
Officer
Gerald T. Proehl serves as our President and Chief Executive
Officer and as a director. Mr. Proehl has served in these capacities since
January 2002. From March 2000 through December 2001, Mr. Proehl was our
President and Chief Operating Officer. From April 1999 to March 2000, Mr.
Proehl was our Vice President, Marketing and Business Development. Prior to
joining Santarus, Mr. Proehl was with Hoechst Marion Roussel, Inc., a global
pharmaceutical company, for 14 years, where he served in various capacities in
multiple therapeutic areas including gastrointestinal, cardiovascular, wound
care and central nervous system, and from March 1997 to April 1999 served as
Vice President of Global Marketing. While at Hoechst Marion Roussel, Mr. Proehl
oversaw the co-promotion of the proton pump inhibitor Prilosec® by Hoechst
Marion Roussel and Astra Merck Inc. and was responsible for the marketing of
gastrointestinal products Carafate® and Pentasa®, among products in several
other therapeutic areas. Mr. Proehl holds a B.S. in education from the State
University of New York at Cortland, an M.A. in exercise physiology from Wake
Forest University and an M.B.A. from Rockhurst College.

E. David Ballard II, M.D. Senior Vice President, Clinical
Research and Medical Affairs
E. David Ballard II, M.D. serves as our Senior Vice
President, Clinical Research and Medical Affairs. Dr. Ballard joined Santarus
in March 2004 as Vice President, Clinical Research, was appointed Vice
President, Medical Affairs in September 2005, was promoted to Vice President,
Clinical Research and Medical Affairs in March 2006 and was promoted to his
current position in September 2008. From March 2000 to February 2004, Dr.
Ballard served in various positions at TAP Pharmaceutical Products Inc., a
pharmaceutical company, most recently serving as Therapeutic Area Head,
Gastroenterology and Internal Medicine. From July 1997 to March 2000, Dr.
Ballard was a Medical Director at Abbott Laboratories, a pharmaceutical
company. Dr. Ballard holds a B.S. in biology from Morehouse College and an M.D.
from the Medical College of Ohio. Dr. Ballard is also certified as a
gastroenterologist by the American Board of Internal Medicine.

Debra P. Crawford Senior Vice President, Chief Financial
Officer, Treasurer and Secretary
Debra P. Crawford serves as our Senior Vice President, Chief
Financial Officer, Treasurer and Secretary. Ms. Crawford joined Santarus in
November 2000 as Vice President, Chief Financial Officer, Treasurer and
Secretary and was promoted to her current position in December 2003. Prior to
joining Santarus, Ms. Crawford served as Vice President, Chief Financial
Officer and Treasurer from July 1998 to May 2000 for Women First HealthCare,
Inc., a specialty healthcare company. Ms. Crawford was also Assistant Secretary
of Women First from July 1998 to February 1999 and Secretary from March 1999 to
May 2000. From May 2000 to October 2000 and from March 1997 to August 1998, Ms.
Crawford was self-employed and provided financial consulting services in the
area of corporate development and in the capacity of acting chief financial
officer. Ms. Crawford also served as Chief Financial Officer, Vice President of
Finance and Administration and Treasurer of IVAC Holdings, Inc. from January
1996 to December 1996 and of IVAC Medical Systems, Inc., a medical device
company, from January 1995 to December 1996. From September 1981 to December
1994, Ms. Crawford served in various financial positions within companies of the
medical device division of Eli Lilly & Company. Ms. Crawford is a certified
public accountant and holds a B.S. in business administration from San Diego
State University.

Julie A. DeMeules Senior Vice President, Human Resources
Julie A. DeMeules serves as our Senior Vice President, Human
Resources. Ms. DeMeules joined Santarus in January 2004 as Vice President,
Human Resources and was promoted to her current position in February 2006. From
January 2000 to November 2003, Ms. DeMeules served as Vice President, Human
Resources at Quidel Corporation, a manufacturer and distributor of medical
diagnostic products. From February 1991 to January 2000, Ms. DeMeules was
employed with Advanced Tissue Sciences, a biotechnology company, most recently
serving as Vice President, Human Resources. Prior to joining Advanced Tissue
Sciences, Ms. DeMeules served as Director of Human Resources at Square D
Corporation, a provider of electrical products, from June 1990 to February
1991. Prior to joining Square D Corporation, Ms. DeMeules served for several
years as Vice President of Human Resources of Signet Armorlite, Inc., a
manufacturer and distributor of ophthalmic lenses and supplies. Ms. DeMeules
holds a B.A. in business administration from the University of San Diego and an
M.B.A. from San Diego State University.

William C. Denby, III Senior Vice President, Commercial
Operations
William C. Denby, III serves as our Senior Vice President,
Commercial Operations. Mr. Denby has held this position since he joined
Santarus in February 2002. Prior to joining Santarus, from October 2001 to
February 2002, Mr. Denby served as Senior Vice President of Commercial
Operations of Agouron Pharmaceuticals, Inc., a provider of HIV and other
specialty pharmaceutical products that was acquired by Pfizer Inc. From June
1997 to October 2001, Mr. Denby served as Senior Vice President and Vice
President of Sales and Marketing for Agouron. From January 1995 to June 1997,
Mr. Denby served as Senior Director of Sales and Marketing and Senior Director,
Commercial and Marketing Affairs for Agouron. Prior to that, Mr. Denby was at
Marion Laboratories for 18 years, holding various positions in corporate
finance, strategic planning, and sales and marketing. While at Marion
Laboratories, Mr. Denby was responsible for promoting a diverse product line
which included brands such as Cardizem®, Nicorette® and the duodenal ulcer drug
Carafate, and he helped secure managed care formulary acceptance for these
products. Mr. Denby holds a B.A. in English from the State University of New
York at Fredonia and an M.B.A. from Rockhurst College.

Carey J. Fox Senior Vice President, General Counsel
Carey J. Fox serves as our Senior Vice President, General
Counsel. Ms. Fox joined Santarus as Senior Director, Legal Affairs in March
2002, served as Vice President, Legal Affairs from May 2004 to February 2006,
was promoted to Vice President, General Counsel in March 2006 and was promoted
to her current position in September 2008. Prior to joining Santarus, Ms. Fox
served as Director, Legal Affairs for Elan Pharmaceuticals, Inc., a
pharmaceutical company, from January 2002 to March 2002. Prior to joining Elan,
Ms. Fox was associated with the law firm of Brobeck, Phleger & Harrison LLP
from May 1998 to December 2001 and with the law firm of Fennemore Craig from
January 1996 to May 1998, where she represented a variety of clients in general
corporate and securities law matters. Ms. Fox is a member of the State Bar of
California and holds a B.A. in social ecology from the University of
California, Irvine and a J.D. from Arizona State University.

Warren E. Hall Senior Vice President, Manufacturing and
Product Development
Warren E. Hall serves as our Senior Vice President,
Manufacturing and Product Development. Mr. Hall joined Santarus in July 2001
as Vice President, Manufacturing and Product Development and was promoted to
his current position in December 2003. Prior to joining Santarus, Mr. Hall
served as Senior Director of Development from July 2000 to July 2001 at Dura Pharmaceuticals,
a specialty pharmaceutical company that was acquired by Elan Corporation, plc,
a pharmaceutical company. Mr. Hall served as Senior Director of Program
Management for the pulmonary group at Dura from February 1999 to July 2000, and
as Senior Director of Manufacturing from July 1998 to February 1999. From
November 1995 to June 1998, Mr. Hall served as Director of Manufacturing
Operations at Cell Therapeutics, Inc., a cancer treatment company. Prior to
Cell Therapeutics, Mr. Hall was with Mallinckrodt, Inc., a pharmaceutical and
specialty chemical company, for 17 years, serving in various capacities, most
recently as Director of Worldwide Manufacturing. Mr. Hall holds a B.A. in
chemistry and biology from Greenville College and an M.S. in organic chemistry
from Southern Illinois University.

Michael D. Step Senior Vice President, Corporate
Development
Michael D. Step serves as our Senior Vice President,
Corporate Development. Mr. Step has held this position since he joined
Santarus in February 2005. Prior to joining Santarus, he served from August
2000 to February 2005 with Amylin Pharmaceuticals, Inc., a biopharmaceutical
company, most recently as Vice President, Corporate Development. In this
capacity, he was responsible for leading corporate development activities,
including product licensing, strategic planning, and mergers and acquisitions
evaluations. Prior to Amylin, he was Senior Director, Business Development at
Dura Pharmaceuticals, Inc., a pharmaceutical company, from May 1998 to July
2000. In this position, his duties included licensing of marketed
pharmaceutical products. Prior to that, he served in corporate development and
strategic planning at Hoffmann-La Roche and sales and management roles at Roche
Labs and Syntex Labs. Mr. Step holds a B.A. in political science from
Vanderbilt University and an M.B.A. from the University of Southern California.

Maria Bedoya-Toro, PhD Vice President, Regulatory Affairs
and Quality Assurance
Maria Bedoya-Toro, PhD serves as our Vice President, Regulatory
Affairs and Quality Assurance. Dr. Bedoya-Toro has held this position since she
joined Santarus in May 2007. She previously served as Senior Director
Regulatory Affairs at Eisai Medical Research Inc. from November 2006 to May
2007, moving to Eisai from Ligand Pharmaceuticals, Inc. when Ligand divested
their oncology products to Eisai in November 2006. Dr. Bedoya-Toro worked as
Senior Director Global Regulatory Affairs and Compliance at Ligand from 2003 to
2006. From 2000 to 2003 she served as Director Global Regulatory Affairs at
Baxter Hyland Immuno. From 1998 to 2000 Dr. Bedoya-Toro worked at BASF
Bioresearch Corporation as Director Regulatory Affairs/Quality, and from 1996
to 1998 she worked as Director Quality Assurance and Regulatory Compliance at
Amylin Pharmaceuticals. From 1988 to 1996 Dr. Bedoya-Toro worked at
Rhone-Poulenc Rorer in a number of increasingly responsible positions in
regulatory compliance, quality assurance, quality control and compliance. Dr.
Bedoya-Toro holds an M.B.A from the University of Chicago, a Ph.D. in
bio-analytical chemistry from Ohio University. In addition she has a M.A. in
bio-analytical chemistry and a B.S. in chemistry from Western Michigan
University.

Blake A. Boland Vice President, Sales
Blake A. Boland serves as our Vice President, Sales. Mr.
Boland joined Santarus in January 2004 as Director, National Sales and was
promoted to his current position in July 2004. Prior to joining Santarus, Mr.
Boland was with Aventis Pharmaceuticals, a global pharmaceutical company, for
16 years. From November 1998 to December 2003, Mr. Boland served as a Regional
Sales Director, where he was responsible initially for building a new primary
care sales organization in the western U.S. During his career with Aventis and predecessor
companies, Mr. Boland held various positions in sales, marketing and sales
management in such therapeutic areas as gastroenterology, cardiovascular,
respiratory, diabetes and anti-infectives. Mr. Boland holds a B.A. in business
administration from Graceland College and an M.B.A. from Rockhurst College.

Jonathan M. Hee Vice President, Commercial Affairs
Jonathan M. Hee serves as our Vice President, Commercial
Affairs. Mr. Hee has held this position since he joined Santarus in January
2004. From October 2000 to December 2003, Mr. Hee served as Vice President,
Sales and Marketing Services at Agouron Pharmaceuticals, Inc., a provider of
HIV and other specialty pharmaceutical products that was acquired by Pfizer
Inc. From October 1996 to October 2000, Mr. Hee served as Director and Senior
Director, Sales and Marketing Services for Agouron. Mr. Hee was a Senior
Manager of Segment Marketing for Agouron from November 1995 to October 1996.
Prior to joining Agouron, Mr. Hee was with Gensia Inc., a cardiovascular and
multi-source injectable drug company, where he held various management roles
including Associate Director positions in marketing and market planning. Mr.
Hee holds a B.S. in chemical engineering from Stanford University and an M.B.A.
from Harvard University.

Martha L. Hough Vice President, Finance and Investor Relations
Martha L. Hough serves as our Vice President, Finance and
Investor Relations. Ms. Hough has held this position since she joined Santarus
in January 2005. From August 2002 to December 2004, and September 1998 to
October 1999, Ms. Hough was a self-employed consultant to medical technology
and pharmaceutical companies. From November 1999 to July 2002, Ms. Hough was
Vice President, Business Development, and Chief Financial Officer of LMA North
America, Inc., a profitable private medical device company. From 1987 to 1998,
Ms. Hough worked in various finance, investor relations, and marketing
positions at Gensia Sicor, Inc., serving as Vice President, Finance and
Corporate Communications there from January 1995 to June 1998. Ms. Hough holds
a B.S. in psychology from Colorado State University and an M.B.A. from the Tuck
School of Business at Dartmouth College.

Thomas J. Joyce Vice President, Marketing and National Accounts
Thomas J. Joyce serves as our Vice President, Marketing and
National Accounts. Mr. Joyce has held this position since he joined Santarus in
January 2004. From April 2002 to January 2004, Mr. Joyce served as Senior
Director, Marketing at Neurocrine Biosciences, Inc., a drug discovery and
development company. From July 1999 to March 2002, Mr. Joyce served as Senior
Director, Global Marketing Planning of Agouron Pharmaceuticals, Inc., a
provider of HIV and other specialty pharmaceutical products that was acquired
by Pfizer Inc. From September 1997 to June 1999 and from May 1996 to August
1997, Mr. Joyce served as Associate Director of Corporate Development and
Senior Market Manager, respectively, of Agouron. Prior to joining Agouron, Mr.
Joyce held various sales and sales management positions at Hoechst Marion
Roussel. Mr. Joyce holds a B.A. in psychology from the University of Dayton.